Rapid spectrophotometric determination of benzalkonium in pharmaceuticals by extraction/FIA.

Sensitive ultraviolet spectrophotometric determination of quetiapine fumarate in pharmaceuticals

Quetiapine fumarate (QTF) is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives indicated for the treatment of schizophrenia. It is a selective monoaminergic antagonist with high affinity for the serotonin type 2 (5HT2), and dopamine type 2 (D2) receptors. Two simple, sensitive, selective, economical and reproducible UV spectrophotometric methods are described for...

Spectrophotometric determination of ofloxacin in pharmaceuticals and human urine

Three simple and sensitive spectrophotometric methods are described for the determination of ofloxacin (OFX) in pharmaceuticals and in spiked human urine. First and second methods are based on the measurement of absorbance of OFX in 0.1 M HCl at 293 nm (method A) and 0.1 M NaOH at 287 nm, respectively. The third method is based on the measurement of 2:1 complex formed between OFX and iron(III) ...

Titrimetric and spectrophotometric determination of lamivudine in pharmaceuticals

Three new methods are described for the assay of lamivudine in bulk drug and in tablet dosage forms using chloramine-T and two dyes, methyl orange and indigo carmine, as reagents. In titrimetry, aqueous solution of lamivudine is treated with a measured excess of chloramine-T in sulphuric acid medium and after the oxidation of lamivudine is judged to be complete, the unreacted oxidant is determi...

Spectrophotometric Determination of Fexofenadine Hydrochloride and Betamethasone in Pharmaceuticals Section 1 Spectrophometric Determination of Fexofenadine Hydrochloride in Phrmaceuticals Section Ii Spectrophotometric Determination of Betamethasone in Pharmaceuticals

Selective Spectrophotometric Determination of Metformin Hydrochloride in Pharmaceuticals and Urine Using Two Nitrophenols as Chromogenic Agents

      Metformin hydrochloride (MFH) is an oral anti-diabetic drug of biguanide class. Two selective spectrophotometric methods were presented for the determination of MFH in pharmaceuticals. The methods were based on the measurement of yellow-coloured charge-transfer complexes formed between MFH and two poly-nitrophenols, namely, 2,4-dinitrophenol (DNP method, at 405 nm) and picric acid (PA met...